Actually I've been watching the program again recently and it discusses Sherlock Holmes and his use - get this - of cocaine! According to the History Channel show (~"Illegal drugs and how they got that way: Cocaine") cocaine was developed around the 1860s and was initially used as a pick-me-upper in a variety of things such as wine and Coca Cola. From what I understand it was considered to be a hyper-equivalent of a cup of coffee, though it had some big side effects.
The show goes into how the drug was brought down and made illegal. It had been given to black dock workers to help them avoid fatigue, but eventually the general fear became that it made blacks more aggressive toward white women. Apparently this was the last draw and the crack down began (I believe in the 19-teens). Rather a sad story of race relations in the U.S., and also sad that a drug which was used on a race to keep them working longer ended up capturing many with addiction in the decades since.